3- (IMIDAZOLYL) -2-ALCOXYPROPIONIC ACIDS AS TAFIA INHIBITORS (THROMBIN-ACTIVATED FIBRINOLYSIS INHIBITOR)

摘要

The compounds of formula (I), where n is 0-3, R 1 is a possibly substituted C 1-6 alkyl, C 1-6 alkenyl or C 1-6 alkynyl, a heterocycle, an aromatic heterocycle, aryl or hydrogen, and R, R, R, R, R, R, R and R each independently is selected from hydrogen and optionally substituted C 1-6 alkyl or R 8 and R 12 represent an alkylene chain are new. They are useful in the treatment of thrombotic conditions and other pathologies associated with fibrin deposition. The international application was published along with an international search report.