COMPLEXES OF E-2- METHOXY -N- (3-{4- 3-METHYL -4-(6-METHYL- PYRIDIN -3-YLOXY) -PHENYLAMINO -QUINAZOLIN -6-YL} -ALLYL)- ACETAMIDE, THEIR METHOD OF PRODUCTION, AND USE.

摘要

The invention relates to complexes of E-2- Methoxy-N -(3- {4-[3-methyl -4-(6-methyl - pyridine -3-yloxy) -phenylamino] -quinazolin -6-yl} -allyl)-acetamide having the following formula I: The invention also relates to pharmaceutical compositions containing the complexes of formula I. The invention further relates to methods of treating hyperproliferative diseases, such as cancers, in mammals, especially humans by administering the above complexes and to methods of preparing the above complexes.