Crystalline Polymorph II (2S, 3S, 5S) - 5 - N - N - N - methyl - N - (2 - isopropyl - 4-thiazolyl) methyl amino carbonyl - L - valinil amino - 2 - (5 - N - (Methoxycarbonyl 2-amino-4-thiazolyl) amino - 1,6 - Diphenyl - 3 - hidroxihexano (ritonavir); Preparation procedure; Pharmaceutical composition useful for the inhibition of HIV Protease.

摘要

The present invention relates to substantially pure amorphous ritonavir and a process for the preparation thereof. The invention also relates to a process for the praparation of the substantially pure ritonavir crystalline polymorph Form I. IMAGE