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FRAGMENT DNA, VECTOR AND MICROORGANISM CONTAINING GENES FOR BUTYROBETAINE/CROTONOBETAINE-L-CARNITINE METABOLISM AND PROCESS FOR PRODUCING OF L-CARNITINE
FRAGMENT DNA, VECTOR AND MICROORGANISM CONTAINING GENES FOR BUTYROBETAINE/CROTONOBETAINE-L-CARNITINE METABOLISM AND PROCESS FOR PRODUCING OF L-CARNITINE
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机译:酪氨酸丁二酸/巴豆糖原-L-肉碱代谢的基因片段,含有矢量和微生物的基因以及L-肉碱的生产工艺
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PCT No. PCT/EP94/03317 Sec. 371 Date Jul. 2, 1996 Sec. 102(e) Date Jul. 2, 1996 PCT Filed Oct. 7, 1994 PCT Pub. No. WO95/10613 PCT Pub. Date Apr. 20, 1995An isolated DNA fragment including the genes bcoC, bcoA/B, bcoD coding for the enzymes for L-carnitine biosynthesis in gamma -butyrobetaine/crotonobetaine metabolism and, additionally, including the gene bcoT coding for a potential transport protein in gamma -butyrobetaine/crotonobetaine metabolism. Also, any vector which includes an isolated DNA fragment including the genes bcoC, bcoA/B, bcoD coding for the enzymes for L-carnitine biosynthesis in gamma -butyrobetaine/crotonobetaine metabolism and, additionally, including the gene bcoT coding for a potential transport protein in gamma -butyrobetaine/crotonobetaine metabolism. Also, biotechnological process for the production of L-carnitine characterized in that crotonobetaine and/or gamma -butyrobetaine is fermented in the presence of a suitable carbon and nitrogen source using a microorgansim and L-carnitine is isolated.
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