Active substance combination containing an opioid having a fentanyl-type structure and ketamine

摘要

A combination of active ingredients consisting of: a) at least one opioid compound with a fentanyl-type structure and/or one of its enantiomers and/or one of its diastereoisomers and/or a corresponding physiologically tolerable salt and b) ketamine and/or at least one of its physiologically tolerable salts, in which the weight ratio of active component a) to active component b) is in the range of 1:350 to 1:550, is disclosed. The opioid compound with a fentanyl-type structure may be a compound of general formula I. The combination described may be useful in treating pain. In particular, it may be useful for controlling neuropathic pain or acute pain.