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NEW STABILIZED GALENSE FORMULATIONS COMPOSING A BENZIMIDAZOLE LABIL ACID COMPOUND AND ITS PREPARATION

机译:含有苯并咪唑唑酸化合物的稳定化新加仑制剂及其制备

摘要

New stable galenic formulations containing an acid-labile benzimidazol compound, and production process. Said formulations comprise a neutral nucleus on which is applied a layer containing the active ingredient and comprised of the benzimidazol compound having the general formula (I), a water-soluble polymer and non-alkaline reaction vehicles, and on which is applied a second isolating layer which comprises a water-soluble polymer, a pigment and talcum, and a last enteric layer which contains a polymer, a plastifier and talcum. CHEM
机译:含有对酸不稳定的苯并咪唑化合物的新型稳定的加仑制剂和生产工艺。所述制剂包含中性核,在其上施加包含活性成分的层,该层由具有通式(I)的苯并咪唑化合物,水溶性聚合物和非碱性反应介质组成,并在其上施加第二分离物。包含水溶性聚合物,颜料和滑石的层,以及包含聚合物,增塑剂和滑石的最后肠溶层。 <化学>

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