Beta-carboline derivatives with hypnotic activity, method for their preparation and a medicament containing thereof

摘要

Described are beta-carboline derivatives of general formula (Ia) (Ia' and Ia'') with meaning of substituents mentioned in claims 1 to 4. Described is also the method for the preparation of the derivatives as well as the intermediate products thereof. Beta-carboline derivatives are active ingredients of the medicament used for the treatment of diseases associated with disorders of melatonin activity, for the treatment of depression and psychiatric disorders, in particular stress, anxiety, depression, insomnia, schizophrenia, psychoses and epilepsy, for the treatment of sleeping disorders associated with travelling, neurodegenerative diseases of the central nervous system for the treatment of cancer.