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Platinum complex in oxidation number IV, process for its preparation, this complex as medicament and pharmaceutical composition containing this complex
Platinum complex in oxidation number IV, process for its preparation, this complex as medicament and pharmaceutical composition containing this complex
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机译:氧化数为IV的铂配合物,其制备方法,该配合物作为药物和含有该配合物的药物组合物
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摘要
Platinum complex of general formula (I). There is also disclosed a process for the manufacture of the complex of formula (I) based on oxidation of a complex of divalent platinum of formula (II) with hydrogen peroxide and on optional substitution of hydroxyl groups in the obtained product with carboxylate groups by action of an acylating agent. The disclosed complexes may be used as such or as a part of pharmaceutical compositions in a therapy of oncological diseases.
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