composition comprising an amorphous solid dispersion of a glycogene phosphorylase inhibitor and method for its preparation

摘要

the invention relates to pharmaceutical compositions comprising a solid amorphous dispersion of 1 [(s) - benzyl - (2r) - hydroxy - 3 - (3r, 4s) - dihydroxy - pyrrolidine - yl) - 3 - oxypropyl] acid amide 5 - chloro - 2 - 1h indole carboxylic acid in the polymer to increase of concentration. it is also the process for their preparation, and dosage forms containing them.application: use for the suppression of hepatic glucose production.