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MUTANT VARIANT OF INSULIN-LIKE GROWTH FACTOR-I (IGF-I)
MUTANT VARIANT OF INSULIN-LIKE GROWTH FACTOR-I (IGF-I)
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机译:胰岛素样生长因子-I(IGF-I)的突变型
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摘要
IGF-I variants having an alanine, glycine, or serine amino acid residue at position 16, 25, 49 or at positions 3 and 49 of native-sequence IGF-I are provided that are useful to treat a disorder characterized by dysregulation of the GH/IGF axis in a mammal, such as a renal disorder.
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