PHARMACEUTICAL PREPARATIONS WITH A COMBINATION OF AT LEAST ONE REPRESENTATIVE OF THE ANTIBIOTICS AND ANTIPHLOGISTICS, PROCESS FOR THEIR PRODUCTION AND THEIR USE

摘要

Pharmaceutical composition (C1) comprises a salt of an antibiotic (I), namely gentamicin, clindamycin, neomycin, streptomycin, tetracycline, doxycycline, oxytetracycline or rolitetracycline, with an antiinflammatory agent (II), namely ibuprofen, naproxen, indomethacin, dexamethasone 21-phosphate, dexamethasone 21-sulfate, triamcinolone 21-phosphate or triamcinolone 21-sulfate. Independent claims are also included for: (1) pharmaceutical composition (C2) comprising tablets or pellets formed from a mixture of a water-soluble salt of (I), a water-soluble salt of (II) and an excipient; (2) production of C1 by the action of water or an aqueous medium on C1 to form a sparingly water-soluble antiinflammatory-antibiotic salt in the tablets or pellets.