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Analytical method for the diagnosis of AIDS and related use of monoclonal antibodies.

机译:诊断艾滋病的分析方法以及单克隆抗体的相关用途。

摘要

Analytical method for the diagnosis of AIDS and related use of monoclonal antibodies.; The analytical method is based on the different level of expression of the molecule HLA-G that takes place on the surface of monocytes and lymphocytes from peripheral blood of healthy individuals and infected with HIV-1 individuals, and includes the evaluation by flow cytometry percentage of said monocytes and / or lymphocytes expressing said molecule HLA-G in the individual analyzed.; Furthermore, the use of specific monoclonal antibodies against HLA-G molecule to sensitize said monocytes and / or lymphocytes from AIDS patients, compared to cytotoxic immune cells.; Application in the diagnosis and treatment of AIDS.
机译:诊断艾滋病的分析方法以及单克隆抗体的相关用途。该分析方法基于健康个体和HIV-1个体感染者外周血单核细胞和淋巴细胞表面HLA-G分子表达水平的不同,并包括流式细胞仪检测在所分析的个体中表达所述分子HLA-G的所述单核细胞和/或淋巴细胞。此外,与细胞毒性免疫细胞相比,使用针对HLA-G分子的特异性单克隆抗体使来自AIDS患者的所述单核细胞和/或淋巴细胞敏感。在艾滋病的诊断和治疗中的应用。

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