GENETIC ANALYSIS FOR STRATIFICATION OF BREAST CANCER RISK

摘要

The present invention provides new methods for the assessment of cancer riskin the general population. These methods utilize particular alleles of two ormore genes, in combination, to identify individuals with increased ordecreased risk of cancer. Exemplified is risk assessment for breast cancer inwomen. In addition, personal history measures such as age and race are used tofurther refine the analysis. Using such methods, it is possible to reallocatehealthcare costs in cancer screening to patient subpopulations at increasedcancer risk. It also permits identification of candidates for cancerprophylactic treatment.