Polar silanes for binding to substrates and use of the bound substrates in chromatography

摘要

Polyfunctional silicon compounds having one of the following structures: wherein at least one of R1, R2 and R3 is a leaving group which, after leaving, permits the Si in one of said structures to form a Si-O-Si or Si-O-Zr bond, wherein L1, L2 and L3 comprise alkyl or substituted alkyl chains from 1 to 100 in length, wherein m = 1-100; wherein N - PG, N - PG1 and N - PG2 are nitrogen-containing polar groups; wherein each of E, E1, and E2 comprise alkyl, substituted alkyl, aryl, or substituted aryl groups, comprising 1-50 carbon atoms, and exclude functional groups selected from the group consisting of hydroxyl, carboxyl, amino, thio, halo and sulfonate moieties. Also, such compounds bound to substrates for use as chromatography.packing.