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ACETOACETYL-COA THIOLASE AND USE OF FOR THE IDENTIFICATION OF NOVEL FUNGICIDAL SUBSTANCES

机译:乙炔-COA硫醇和用于鉴定新型杀真菌物质的用途

摘要

The invention relates to nucleic acids which code for polypeptides from fungi with acetoacetyl-CoA thiolase biological activity, polypeptides coded thereby, use thereof as targets for fungicides and the use thereof for the identification of novel fungicidal compounds. The invention further relates to methods for the discovery of modulators of said polypeptides and hence transgenic organisms comprising sequences coding for polypeptides from fungi with the function of an acetoacetyl-CoA thiolase.
机译:本发明涉及编码来自具有乙酰乙酰辅酶A硫解酶生物活性的真菌的多肽的核酸,由此编码的多肽,其用作杀真菌剂的靶标及其在鉴定新型杀真菌化合物中的用途。本发明进一步涉及发现所述多肽的调节剂的方法,并因此发现转基因生物,其包括编码具有乙酰乙酰辅酶A硫解酶功能的来自真菌的多肽的序列。

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