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PROCESS AND SUPPORTS FOR SYNTHESIS OF PEPTIDES COMPRISING A THIOESTER OR THIOACID
PROCESS AND SUPPORTS FOR SYNTHESIS OF PEPTIDES COMPRISING A THIOESTER OR THIOACID
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机译:包含硫代酯或硫代酸的肽的合成过程和支持
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摘要
A process for the Fmoc synthesis of a peptide comprising a thioester or thioacid which comprises removing the Nalpha-Fmoc blocking group with a base selected from optionally substituted piperazine or optionally substituted 2,6-C1-4dialkyl-piperidine or a mixture thereof. Also novel solid supports suitable for the solid-state synthesis of peptide thioesters and thioacids and processes for making these supports.
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