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METHOD FOR INDUCING SELECTIVE CELL DEATH OF MALIGNANT CELLS BY ACTIVATION OF CALCIUM-ACTIVATED POTASSIUM CHANNELS (KCA)
METHOD FOR INDUCING SELECTIVE CELL DEATH OF MALIGNANT CELLS BY ACTIVATION OF CALCIUM-ACTIVATED POTASSIUM CHANNELS (KCA)
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机译:钙激活钾通道(KCA)的激活诱导恶性细胞选择性细胞死亡的方法
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摘要
Disclosed are a method of inducing apoptosis of a malignant cell, which employs a calcium-activated postassium channel (KCa) activator and is useful for treating a malignant tumor in a human subject. Also disclosed are methods of selectively inhibiting the proliferation of malignant cells compared to non-malignant cells in a mixed population of malignant and non-malignant cells and of inhibiting the growth of a malignant tumor, such as a glial tumor, in a mammalian subject. A kit for inducing apoptosis of malignant cells is also disclosed.
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