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USE OF 5-HT2C RECEPTOR ACTIVITY AFFECTING COMPOUNDS FOR TREATING IDIOPATHIC HYPERHIDROSIS AND ASSOCIATED CONDITIONS
USE OF 5-HT2C RECEPTOR ACTIVITY AFFECTING COMPOUNDS FOR TREATING IDIOPATHIC HYPERHIDROSIS AND ASSOCIATED CONDITIONS
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机译:5-HT2C受体活性影响化合物在治疗特发性多汗症及相关疾病中的应用
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摘要
The subject invention provides methods for treating symptoms and/or conditions associated with idiopathic hyperhidrosis by using compounds that decrease the activity of serotonin 5-HT2C receptors. Compounds that can ameliorate symptoms of idiopathic hyperhidrosis and associated conditions include 5-HT2C receptor antagonists (i.e., ketanserin, ritanserin, mianserin, mesulergine, cyproheptadine, fluoxetine, mirtazapine, olanzapine, and ziprasidone) as well as 5-HT2C receptor modulators (i.e., inverse agonists, partial agonists, and allosteric modulators).
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