首页> 外国专利> DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH HUMAN TRANSMEMBRANE SERINE PROTEASE 3 (TMPRSS3)

DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH HUMAN TRANSMEMBRANE SERINE PROTEASE 3 (TMPRSS3)

机译:与人类跨膜丝氨酸蛋白酶3(TMPRSS3)相关的疾病的诊断和治疗

摘要

The invention provides a human TMPRSS3 which is associated with the cardiovascular disorders, neurological disorders, endocrinological diseases, gastroenterological diseqases, urological disorders, metabolic dieases, cancer, respiratory diseases, hematological diseases and inflammation. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular disorders, neurological disorders, endocrinological diseases, gastroenterological diseqases, urological disorders, metabolic dieases, cancer, respiratory diseases, hematological diseases and inflammation. The invention also features compounds which bind to and/or activate or inhibit the activity of TMPRSS3 as well as pharmaceutical compositions comprising such compounds.
机译:本发明提供了人TMPRSS3,其与心血管疾病,神经疾病,内分泌疾病,肠胃疾病,泌尿科疾病,代谢性疾病,癌症,呼吸系统疾病,血液病和炎症有关。本发明还提供了用于鉴定可用于治疗或预防心血管疾病,神经疾病,内分泌疾病,肠胃疾病,泌尿科疾病,代谢性疾病,癌症,呼吸道疾病,血液病和炎症的化合物的测定法。本发明的特征还在于结合和/或激活或抑制TMPRSS3活性的化合物以及包含此类化合物的药物组合物。

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