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DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH HUMAN TRANSMEMBRANE SERINE PROTEASE 3 (TMPRSS3)
DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH HUMAN TRANSMEMBRANE SERINE PROTEASE 3 (TMPRSS3)
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机译:与人类跨膜丝氨酸蛋白酶3(TMPRSS3)相关的疾病的诊断和治疗
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摘要
The invention provides a human TMPRSS3 which is associated with the cardiovascular disorders, neurological disorders, endocrinological diseases, gastroenterological diseqases, urological disorders, metabolic dieases, cancer, respiratory diseases, hematological diseases and inflammation. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular disorders, neurological disorders, endocrinological diseases, gastroenterological diseqases, urological disorders, metabolic dieases, cancer, respiratory diseases, hematological diseases and inflammation. The invention also features compounds which bind to and/or activate or inhibit the activity of TMPRSS3 as well as pharmaceutical compositions comprising such compounds.
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