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DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH HUMAN TRANSMEMBRANE SERINE PROTEASE 2 (TMPRSS2)
DIAGNOSTICS AND THERAPEUTICS FOR DISEASES ASSOCIATED WITH HUMAN TRANSMEMBRANE SERINE PROTEASE 2 (TMPRSS2)
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机译:与人类跨膜丝氨酸蛋白酶2(TMPRSS2)相关的疾病的诊断和治疗
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摘要
The invention provides a human TMPRSS2 which is associated with the cardiovascular disorders, endocrinological diseases, gastroenterological diseqases, metabolic diseases, cancer, respiratory diseases, urological disorders and inflammation. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular disorders, endocrinological diseases, gastroenterological diseqases, metabolic diseases, cancer, respiratory diseases, urological disorders and inflammation. The invention also features compounds which bind to and/or activate or inhibit the activity of TMPRSS2 as well as pharmaceutical compositions comprising such compounds.
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