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BIODEGRADABLE MEMBRANE-COVERED IMPLANT COMPRISING CHITOSAN

机译:包含壳聚糖的可生物降解膜覆盖植入物

摘要

The present invention relates to medical implants such as stents, which can be coated with a biodegradable membrane containing or not an active ingredient or medicament, their method of preparation and their use. The present invention provides for a biodegradable membrane covered endovascular device. The device is coated with a solution comprising chitosan and chitosan plasticizer or cross-linker, the solution which when dried thereon, upon rehydration, forms a flexible polymeric membrane on the device, or which when freeze-dried thereon, forms upon rehydration a porous flexible polymeric membrane.
机译:本发明涉及可以用含有或不含活性成分或药物的可生物降解膜包被的医疗植入物,例如支架,其制备方法和用途。本发明提供了一种可生物降解的膜覆盖的血管内装置。该装置涂覆有包含脱乙酰壳多糖和脱乙酰壳多糖增塑剂或交联剂的溶液,该溶液在干燥时在水合后在装置上形成柔性聚合物膜,或者在冻干后在水合时形成多孔的柔性膜。聚合物膜。

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