METHOD FOR TREATING CANCER BY VECTOR-MEDIATED DELIVERY OF ONE OR MORE ANTI-ANGIOGENIC OR PRO-APOPTOTIC GENES

摘要

The present invention provides therapeutic compositions and methods for vector-mediated delivery and in vivo expression of polynucleotides encoding anti-cancer compounds that are effective in the treatment of cancer. In particular, the invention relates to the use of recombinant viral and non-viral vectors to deliver genes encoding one or more anti-angiogenic or proapoptotic gene products for the treatment of cancer.