首页> 外国专利> FUCOSYL GM1-KLH CONJUGATE VACCINE AGAINST SMALL CELL LUNG CANCER

FUCOSYL GM1-KLH CONJUGATE VACCINE AGAINST SMALL CELL LUNG CANCER

机译:岩藻糖基GM1-KLH联合小细胞肺癌疫苗

摘要

This invention provides for a composition comprising a fucosyl GM1 ganglioside or an oligosaccharide thereof conjugated to an immunogenic protein, an adjuvant, the amounts thereof being effective to stimulate or enhance antibody production in a subject, and a pharmaceutically acceptable carrier. This invention also provides a method of stimulating antibody production in a subject which comprises administering to the subject an effective amount of the above-described composition to stimulate antibody production. This invention also provides a method of enhancing antibody production in a subject which comprises administering to the subject an effective amount of the above-described composition to enhance antibody production. This invention also provides a method of preventing cancer in a subject which comprises administering to the subject an amount of the above-described composition effective to prevent cancer. This invention also provides a method of treating cancer in a subject which comprises administering to the subject an amount of the above-described composition effective to treat cancer.
机译:本发明提供了一种组合物,其包含与免疫原性蛋白质缀合的岩藻糖基GM1神经节苷脂或其寡糖,佐剂,其量可有效刺激或增强受试者的抗体产生,以及药学上可接受的载体。本发明还提供了一种刺激受试者中抗体产生的方法,该方法包括向受试者施用有效量的上述组合物以刺激抗体产生。本发明还提供了一种在受试者中增强抗体产生的方法,该方法包括向受试者施用有效量的上述组合物以增强抗体产生。本发明还提供了一种预防受试者癌症的方法,该方法包括给受试者施用一定量的上述有效预防癌症的组合物。本发明还提供了一种治疗对象的癌症的方法,该方法包括向该对象施用有效治疗癌症的一定量的上述组合物。

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