DIAGNOSTIC METHODS , PROGNOSTIC METHODS AND PHARMACEUTICAL COMPOSITIONS FOR NEURODEGENERATIVE DISEASES LIKE ALZHEIMER’S DISEASE BY MODULATING AND INVESTIGATING GENES RGS4 AND ITPKB, THEIR GENE PRODUCTS OR FRAGMENTS AND DERIVATIVES THEREOF

摘要

The present invention relates to diagnostic and prognostic methods for Alzheimer's Disease. The methods comprise measuring altered expression levels of the genes RGS4 and ITPKB in samples from a subject. The inventions also relate to kits for performing the method, and methods for screening for agents modulating expression of RGS4 and/or ITPKB, as well as the use of such agents for treating Alzheimer's Disease and manufacturing pharmaceutical compositions.