SEQUENTIAL THERAPY COMPRISING A 20(S)-CAMPTOTHECIN COMPOUND AND A PYRIMIDINE BASE ANALOG

摘要

A method is provided for treating a patient having a disease associated withundesirable or uncontrolled cell proliferation, the method comprising:administering to the patient a 20(S)-camptothecin compound for a period oftime during which a pyrimidine base analog is not being administered to thepatient; and administering a pyrimidine base analog to the patient.