ELICITATION OF ANTIBODIES TO SELF PEPTIDES IN MICE BY IMMUNIZATION WITH DENDRITIC CELLS

摘要

Antibodies are produced by inoculating a host animal with dendritic cells in combination with a self peptide of interest. In one embodiment, antibodies are produced by grafting tissue from one or more human immune organs into an immunodeficient, non-human, mammalian host such as, for example, a SCID mouse and then immunizing the host with a self peptide of interest.