METHOD FOR OPENING TIGHT JUNCTIONS COMPRISING THE USE OF JAM-1, CLAUDIN-4 AND OCCLUDIN PROTEIN ANTAGONISTS AS WELL AS SIRNA MOLECULES

摘要

The use of antagonists to JAM-1 Claudin-4 and occludin to open tight junctions. The antagonists include, by way of example antibodies and antibody fragments that bind to the proteins and small interfering nucleic acids that downregulate the mRNA encoding the proteins.