OGH FUSION POLYPEPTIDES AND THERAPEUTIC USES THEREOF

摘要

A fusion polypeptide comprising an orphan glyprotein hormone (OGH), OGH-family member, or a fragment thereof; a glycoprotein hormone subunit α1 or α2, or a fragment thereof, and optionally a peptide (P), and a fusion component (F). in one embodiment, the fusion protein comprises hOGH-hFc-hα2 or hTSH-hFc-hα1.