EARTHWORM FRIBRINOLYTIC ENZYME GENE, GENETIC ENGINEERING STRAINS, AND THE CONSTRUCTION AND USAGES THEREOF

摘要

The present invention discloses an earthworm fribrinolytic enzyme gene, genetic engineering stains, and the construction and usages thereof. Said fribrinolytic enzyme gene consists of 747 nucleosides, which encodes a protein of 246 amino acid. This gene can be expressed in Pichia pastoris into an active genetic engineering fribrinolytic protease. The present invention further discloses the wide applications of said genetic engineering fribrinolytic protease for drugs development in the areas of therapeutic, healthy, and medical cares.