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Process for producing aromatic compound derivative by reaction of aromatic compound substituted with sulfamoyloxy, sulfinamoyloxy, or carbamoyloxy group, with nucleophilic agent

机译:通过被氨磺酰氧基,亚氨磺酰氧基或氨基甲酰氧基取代的芳族化合物与亲核试剂反应制备芳族化合物衍生物的方法

摘要

A process for producing a compound represented by the following formula (I), which includes causing a compound represented by formula (II) to react with a nucleophilic agent: wherein X represents a substituent; R1 represents an electron-withdrawing substituent having a Hammett σp constant of more than 0; m represents an integer of 1 to 5; R2 represents a substituent; n represents an integer of 0 to 4; and m + n is from 1 to 5; wherein R1, m, R2, and n each have the same meanings to those in formula (I); R3 and R4 each independently represent an alkyl, aryl, or heterocyclic group; and Z represents C=O or S(O)p, wherein p is 1 or 2.
机译:一种由下式(I)表示的化合物的制备方法,其包括使由式(II)表示的化合物与亲核试剂反应: <图像文件=“ IMGA0001.GIF” he =“ 36” id =“ ia01” imgContent =“ chem” imgFormat =“ GIF” wi =“ 41” /> 其中X代表取代基; R 1表示哈米特σ p 常数大于0的吸电子取代基。 m表示1〜5的整数。 R2代表取代基; n为0〜4的整数。 m + n为1至5; <图像文件=“ IMGA0002.GIF” he =“ 39” id =“ ia02” imgContent =“ chem” imgFormat =“ GIF” wi =“ 51” /> 其中R1 ,m,R 2和n分别具有与式(I)相同的含义; R 3和R 4各自独立地表示烷基,芳基或杂环基; Z表示C = O或S(O) p ,其中p为1或2。

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