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METHOD OF ANALYZING NON-COMPLEXED FORMS OF PROSTATE SPECIFIC ANTIGEN IN A SAMPLE TO IMPROVE PROSTATE CANCER DETECTION

机译:分析样品中前列腺特异性抗原的非复杂形式以改善前列腺癌的检测方法

摘要

Chemical examination detection determines that there are prostate cancers to be provided. Test can man group in detection prostate cancer have significantly higher Free PSA and t-PSA. The test can also man group in detect prostate cancer content it is lower, t-PSA in 2 to 4 ranges (that is, reach. An embodiment according to the present invention, test is comprising steps of t-PSA contained in (a) quantitative biological sample determines the sample of the Free PSA of amount from patient (two); With. Calculate the Free PSA and t-PSA of the ratio, (step c) determines the amount of pPSA in the sample, it determines (amount of step d) BPSA in the sample, (5) determine include in the amount and sample of the amount f correlations inPSA of inPSA in sample there are the patients of prostate cancer, by comparing the amount and predetermined value of inPSA, establish the control sample with known cancer and benign disease diagnosis, based on t-PSA it is horizontal all with free PSA.
机译:化学检查检测确定存在要提供的前列腺癌。测试可曼组在检测前列腺癌中具有明显更高的游离PSA和t-PSA。该测试还可以检测其较低的前列腺癌含量,t-PSA在2至4范围内(即达到)。根据本发明的一个实施方案,测试包括(a)中包含的t-PSA步骤定量生物学样品确定了来自患者的游离PSA的量(两个);用。计算游离PSA和t-PSA的比例,(步骤c)确定样品中pPSA的量,它确定了(量步骤d)样品中的BPSA,(5)确定样品中是否存在前列腺癌患者,其中inPSA中的pPSA的相关量与样品中的f相关性,通过比较inPSA的量和预定值,建立对照样品根据已知的癌症和良性疾病诊断,基于t-PSA的情况与免费PSA都是水平的。

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