DETECTING THE RISK OF CARDIOVASCULAR DISEASES BY DETECTING MUTATIONS IN GENES, INCLUDING GENES ENCODING A2B-ADRENOCEPTOR AND APOLIPOPROTEIN B

摘要

The present invention provides a kind of method for identify main body to the sensibility of cardiovascular disease or the risk of developing myocardial infarction (MI) or cerebrovascular stroke by the point mutation of a biology sample detection gene pleiomorphism and other genes from main body and optionally about the acquisition information and case history of family, the analyte of blood, the slurries of main body, plasma and uropoiesis. It is detected in some genes, genetic variations or polymorphic include the gene for encoding a2b- adrenocepters and apolipoprotein B. The present invention also provides a multivariate model, combination or the algorithm of variable, is best described by the probability of cardiovascular disease, especially MI and stroke. The invention further relates to a test kit and softwares, for realizing method.