首页>
外国专利>
NONHUMAN MODEL ANIMAL SUFFERING FROM GUILLAIN-BARRE SYNDROME AND/OR FISHER SYNDROME
NONHUMAN MODEL ANIMAL SUFFERING FROM GUILLAIN-BARRE SYNDROME AND/OR FISHER SYNDROME
展开▼
机译:吉兰-巴雷氏综合症和/或费雪氏综合症的非人类动物模型
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention intends to provide a non-human animal model of Guillain-Barré syndrome, which can be obtained by immunizing FcγRIIB-gene-deficient non-human animal with ganglioside GQ1b, and a screening method of a therapeutic agent for Guillain-Barré syndrome using the non-human animal model. A mouse model of Guillain-Barré syndrome is generated by immunizing FcγRIIB-gene-deficient mice with gangliosides GM1, GM2, GD1a, and GQ1b together with Freund's adjuvant every three weeks four times in total.
展开▼