PREPARING METHOD OF SUSTAINED RELEASE TYPE TAMSULOSIN TABLETS RESULTING IN NO ORGANIC SOLVENT REMAINING AND HIGH DENSITY AT THE END OF DRYING PROCESS AND THE TABLET PREPARED THEREBY

摘要

PURPOSE: A preparing method of sustained release type tamsulosin tablets and the tablet prepared thereby are provided, thereby resolving problems of conventional method such as organic solvent remaining and high density at the end of drying process, and evenly distributing drugs into the tablets. CONSTITUTION: The preparing method of sustained release type tamsulosin tablets comprises the steps of: (a) dissolving tamslosin chloride in solvent, dissolving first phthalic acid hydroxypropylmethylcellulose into the tamslosin chloride dissolved solution to prepare a conjugate solution; (b) adding the conjugate solution into a diluent solution comprising second phthalic acid hydroxypropylmethylcellulose and glyceryldibehenate and assembling them; and (c) optionally drying the assembled mixture, wherein the solvent is at least one selected from ethanol, methylene chloride and water.