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IBUPROFEN AND DEXIBUPROFEN MICRO EMULSION COMPOSITION AND LIQUID MEDICINE AND SOFT CAPSULE DRUG THEREOF

机译:布洛芬和右旋布洛芬的微乳组合物及其液体药物和软胶囊药物

摘要

The present invention is an invention relating to a transparent liquid, and the transparent soft capsule formulation using the same as ibuprofen and the deck of the bitter propene microemulsion containing an antioxidant, more particularly emulsifiers, surfactants, antioxidants, including the antioxidant synergy claim It relates to a transparent liquid, and the transparent soft capsule preparation of ibuprofen and deck microemulsion compositions of bitter propene and using the same.; The composition according to the present invention Chemistry microemulsion formulations using two or more surfactants, and, by adding an antioxidant to the here was to improve the stability and the dissolution rate of the formulation at the same time, further with an antioxidant synergy claim ball higher effect could.; The formulation of the present invention are not only stable at low pH, unlike conventional drugs not cause precipitation of the substance. Also has a feature having a higher dissolution rate than conventional formulations, and were easy to take a small capacity, by reducing the amount of excipients.
机译:本发明涉及一种透明液体,以及使用该透明液体的透明软胶囊制剂,其与布洛芬和含有抗氧化剂,特别是乳化剂,表面活性剂,抗氧化剂的苦丙烯微乳液的甲板有关,包括抗氧化剂协同作用。制成透明液体,以及布洛芬的透明软胶囊制剂和苦味丙烯的甲板微乳液组合物并使用它们。根据本发明的组合物使用两种或更多种表面活性剂的化学微乳液制剂,并且通过向其中加入抗氧化剂来同时提高制剂的稳定性和溶解速度,进一步具有更高的抗氧化剂协同作用效果可以。本发明的制剂不仅在低pH下是稳定的,不同于常规药物不会引起该物质沉淀。还具有比常规制剂具有更高的溶出速率的特征,并且通过减少赋形剂的量易于吸收小容量。

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