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HEK293 CELL LINE FOR ACTIVITY STUDIES AND HTS SYSTEM OF alpha1G T-TYPE CA2+ CHANNEL
HEK293 CELL LINE FOR ACTIVITY STUDIES AND HTS SYSTEM OF alpha1G T-TYPE CA2+ CHANNEL
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机译:HEK293细胞系用于alpha1G T型CA2 +通道的活性研究和HTS系统
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摘要
There is provided a cell line that is prepared by transforming HEK293 cell with a human Kir2.1 gene using a retrovirus expression system, wherein the HEK293 expresses a stable alphaSUB1G /SUBT-type calcium channel. The cell line responds sensitively to KCl and forms an appropriate level of the membrane voltage so that the cell signaling pathway may be investigated by the molecular biological and biochemical studies.
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