A ANTIINFLAMMATORY COMPOSITION CONTAINING STYLOPINE ISOLATED FROM LEAF OF CHELIDONIUM MAJUS

摘要

The present invention relates to anti-inflammatory compositions of Chelidonium (Papaveraceae, Chelidonium majus L. (Papaveraceae)) pin (stylopine) as a still isolated from leaves of an active ingredient. More specifically, the compositions contain the pin to the steel, as an active ingredient, the nitrogen monoxide (NO), prostaglandin _{E 2 (prostaglandin E 2, PGE} 2), tumor necrosis factor -α (tumor necrosis factor-α, TNF-α ), interleukin -1β (interleukin-1β, IL-1β) and IL-6 production, inducible nitric oxide synthase (inducible nitric oxide synthase (iNOS)) and cycloalkyl-oxy agent or claim -2 (cyclooxygenase, COX-2)) inhibiting the expression and shows the anti-inflammatory response.