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New selective inhibition of viral or bacterial neuraminidase

机译:新的选择性抑制病毒或细菌神经氨酸酶

摘要

Novel compounds are described. These compounds have groups which have acidic groups, basic groups, substituted amino or N-acyl groups and optionally hydroxylated alkane moieties. Pharmacological compositions containing inhibitors of the invention are also described. Also described are methods of inhibiting neuraminidase in a sample that is believed to contain neuraminidase. Assays for screening conjugates, antibodies, polymers, antigenic substances and neuraminidase activity of labeled compounds of the invention are also described.
机译:描述了新型化合物。这些化合物具有的基团具有酸性基团,碱性基团,取代的氨基或N-酰基基团和任选地羟基化的烷烃部分。还描述了含有本发明抑制剂的药理组合物。还描述了抑制被认为含有神经氨酸酶的样品中神经氨酸酶的方法。还描述了用于筛选本发明的标记化合物的缀合物,抗体,聚合物,抗原性物质和神经氨酸酶活性的测定法。

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