Process for Preparing Apigenin-7-O-?-D-glucuronide from Clerodendron trichotomum Folium and Composition comprising the compound for the prevention and treatment of gastritis and reversal esophagitis

摘要

The invention clerodendrum trichotomum leaf (Folium Clerodendron trichotomum) Bahia genin -7-O-β-D- glucuronic in Need from; separating the (Apigenin-7-O-β -D-glucuronide hereinafter referred to as "AGC") separation method and the compound related to the gastrointestinal tract inflammation, and the prevention and treatment composition for ulcer and reflux esophagitis, which contains a.; In the present invention, the free which from extracts of Zhangmutou leaf degreased using chloroform, ether, methylene chloride, and then, a non-ionic use of the exchange resin to remove the sugars and inorganic salts, and Sephadex LH 20 with plenty of pure AGC through a second column with a to be obtained, and provides two separate AGC is gastritis and exhibits excellent therapeutic effects than existing drugs in reflux esophagitis and gastritis useful medicines and dietary supplements in the prevention and treatment of gastroesophageal reflux disease.