首页> 外国专利> Process for Preparing Quercetin-3-O-?-D-glucuronide QGC isolated from Rumex Aquaticus Herba and Composition comprising the compound for the prevention and treatment of gastritis diseases and reversal esophagitis

Process for Preparing Quercetin-3-O-?-D-glucuronide QGC isolated from Rumex Aquaticus Herba and Composition comprising the compound for the prevention and treatment of gastritis diseases and reversal esophagitis

机译:分离自Rumex Aquaticus Herba的槲皮素-3-O-β-D-葡萄糖醛酸QGC的制备方法和包含该化合物的组合物,用于预防和治疗胃炎和逆转性食管炎

摘要

The invention foundation sulfur leaf Need as quercetin -3-O-β-D- glucuronic from (Rumex Aquaticus Herba); a method for separating the (Quercetin-3-O-β -D-glucuronide hereinafter QGC D) and the gastrointestinal inflammation containing the compound, to a composition for preventing and treating ulcers and gastroesophageal reflux disease.; In the present invention, was degreased using chloroform, ether, methylene chloride from the extract of the base yellow leaves, and then a non-ionic use of the exchange resin to remove the sugar and inorganic salts and obtain a large amount of pure compound of the through re-crystallization of the 40% fraction obtained and can provide a gastrointestinal inflammation, ulcers, and useful medicines and dietary supplements in the prevention and treatment of gastroesophageal reflux disease exhibits an excellent therapeutic effect than the conventional product is a separate compound in gastritis and acid reflux.
机译:(I)(Rumex Aquaticus Herba)的发明基础硫叶需要的槲皮素-3-O-β-D-葡萄糖醛酸。一种将(槲皮素-3-O-β-D-葡糖醛酸苷,以下称为QGC D)和含有该化合物的胃肠道炎症分离成预防和治疗溃疡和胃食管反流疾病的组合物的方法。在本发明中,使用氯仿,乙醚,二氯甲烷从基础黄叶提取物中脱脂,然后非离子性使用交换树脂去除糖和无机盐,从而获得大量纯净的通过重结晶获得的40%馏分,可以提供胃肠道炎症,溃疡,并且在预防和治疗胃食管反流疾病中比常规产品在胃炎中是单独的化合物,具有优异的治疗效果和酸回流。

著录项

  • 公开/公告号KR100518360B1

    专利类型

  • 公开/公告日2005-09-30

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20020029418

  • 发明设计人 황완균;박선영;손의동;

    申请日2002-05-27

  • 分类号A61K35/78;

  • 国家 KR

  • 入库时间 2022-08-21 22:03:20

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