Monoclonal antibody against asialo ?1-acid glycoprotein, immunochromatographic strip comprising the monoclonal antibody, and method for diagnosing liver diseases using the immunochromatographic strip

摘要

The present invention relates to the field of immunoassays for screening a liver disease. More particularly, the present invention Asai allo α ₁ - acid glycoprotein [hereinafter abbreviated as _{AsAGP (asialo α 1 -acid glycoprotein)} ] monoclonal antibody, using the antibody of the biological sample indicating the specific reactivity to the of how to examine the feasibility of the liver disease by measuring the concentration of AsAGP early, samples of the useful invention in for rapid and examine the disease feasibility between simple early to measure the concentration of AsAGP AsAGP immobilized monoclonal antibody receiving Taunus nose Municipal and GF membrane's agglomerans Ruti Nin (Ricinus communis agglutinin: RCA) for fixing which is characterized containing NC membrane immunochromatography strip, and the upper body that secure the AsAGP monoclonal antibody of the present invention (for example, a micro It relates to a diagnostic kit characterized in that the liver disease, which comprises a plate). Such AsAGP monoclonal antibody of the present invention, the antibody and lectin The immunochromatographic strips, and diagnostic kits for immunological analysis containing RCA Asai allo α ₁ in serum-rapid liver disease glycoproteins acid by measuring the early and it can be easily examined.