A lignan compound and a hypoglycemic agent comprising the lignan compound as active ingredient

摘要

The present invention is excellent in fin thistle separation aid from the hypoglycemic activity (Carduus crispus L.), and a large margin of safety novel compounds: (7R, 8R, 8'R, 9'R) - 4, 7, 4 ', 9 '- tetra-hydroxy-3, 3'-dimethoxy-^{1,3,5,1 ', 3', 5 '8.} 8 ', 9.O. 9 'relates the lignans and the material in a new diabetes drug containing as an active ingredient.; New therapeutic agent for diabetes according to the present invention, the glucose lowering activity as compared to widely used drugs as hypoglycemic agents for conventional oral excellent safety is very high and is also expected to significantly reduce the side effects as compared to conventional drugs.