Therapeutic and prophylactic biological products based on dry biomass bifidobacteria and lactobacilli, biologically active food supplements BASED dry biomass of bifidobacteria and lactobacilli, dry biomass bifidobacteria and lactobacilli AND METHOD FOR ITS PREPARATION

摘要

1.therapeutic and prophylactic biopreparat u0434u043bu00a0 prevention and u043bu0435u0447u0435u043du0438u00a0 u0434u0438u0441u0431u0430u043au0442u0435u0440u0438u043eu0437u043eu0432 and infectious diseases of the gastrointestinal tract in children and adultscontaining the dry biomass of the u0431u0438u0444u0438u0434u043eu0431u0430u043au0442u0435u0440u0438u0439 strain of bifidobacterium adolescentis in - 1 and u043bu0430u043au0442u043eu0431u0430u0446u0438u043bu043b strain of lactobacillus acidophilus at - 41 of the bifidobacterium adolescentis in - 1 from 108 to 1010 some and lactobacillus acidophilus at 41 from 108 to 1010 in some 1 g dry biomassreceived by separate u043au0443u043bu044cu0442u0438u0432u0438u0440u043eu0432u0430u043du0438u00a0 u043bu0438u043eu0444u0438u043bu0438u0437u0438u0440u043eu0432u0430u043du043du044bu0445 cultures of strain of bifidobacterium adolescentis in - 1 synthetic nutritional environment and strain of lactobacillus acidophilus at - 41 organic nutritional environment to further separate the cultivation of renewed cultures, a concentrated liquid obtained from biomass one strain and mixing with a protective environmentthe separate drying method u0441u0443u0431u043bu0438u043cu0430u0446u0438u0438 and mixing of dry biomass, as well as the excipients used in the establishment of fo rm u0434u043bu00a0 u043fu0440u0438u0434u0430u043du0438u00a0 their technological properties, with the following components: ratio of mas.;u0441u0443u0445u0430u00a0 biomass u043au043eu043du0441u043eu0440u0446u0438u0443u043cu0430u0431u0438u0444u0438u0434u043eu0431u0430u043au0442u0435u0440u0438u0439 and u043bu0430u043au0442u043eu0431u0430u0446u0438u043bu043b0,5 - 10,0u0432u0441u043fu043eu043cu043eu0433u0430u0442u0435u043bu044cu043du044bu0435 u0432u0435u0449u0435u0441u0442u0432u0430u043eu0441u0442u0430u043bu044cu043du043eu0435.;2.biologically u0430u043au0442u0438u0432u043du0430u00a0 additive to food u0434u043bu00a0 u0441u043du0438u0436u0435u043du0438u00a0 risk u0440u0430u0437u0432u0438u0442u0438u00a0 u0434u0438u0441u0431u0430u043au0442u0435u0440u0438u043eu0437u043eu0432 gastrointestinal tract as an additional source of u0431u0438u0444u0438u0434u043eu0431u0430u043au0442u0435u0440u0438 first and u043bu0430u043au0442u043eu0431u0430u043au0442u0435u0440u0438u0439 people of different age groupsu0441u043eu0434u0435u0440u0436u0430u0449u0430u00a0 dry biomass of the u0431u0438u0444u0438u0434u043eu0431u0430u043au0442u0435u0440u0438u0439 strain of bifidobacterium adolescentis in - 1 and u043bu0430u043au0442u043eu0431u0430u0446u0438u043bu043b strain of lactobacillus acidophilus at - 41 of the bifidobacterium adolescentis in - 1 from 108 to 1010 some and lactobacillus acidophilus at 41 from 108 to 1010 in some 1 g dry biomassreceived by separate u043au0443u043bu044cu0442u0438u0432u0438u0440u043eu0432u0430u043du0438u00a0 u043bu0438u043eu0444u0438u043bu0438u0437u0438u0440u043eu0432u0430u043du043du044bu0445 cultures of strain of bifidobacterium adolescentis in - 1 synthetic nutritional environment and strain of lactobacillus acidophilus at - 41 organic nutritional environment to further separate the cultivation of crops u043au043eu043du0446u0435u043du0442u0440u0438u0440u043eu0432u0430u043du0438u0435u043c renewed, the obtained liquid biomass obtained one strain and mixing with a protective environmentthe separate drying method u0441u0443u0431u043bu0438u043cu0430u0446u0438u0438 and mixing of dry biomass, as well as the excipients used in the creation of the organic act of u0438u0432u043du044bu0445 additives to food u0434u043bu00a0 u043fu0440u0438u0434u0430u043du0438u00a0 them process and characteristics, with the following components: ratio of mas.;u0441u0443u0445u0430u00a0 biomass u043au043eu043du0441u043eu0440u0446u0438u0443u043cu0430u0431u0438u0444u0438u0434u043eu0431u0430u043au0442u0435u0440u0438u0439 and u043bu0430u043au0442u043eu0431u0430u043au0442u0435u0440u0438u04390,5 - 10,0u0432u0441u043fu043eu043cu043eu0433u0430u0442u0435u043bu044cu043du044bu0435 u0432u0435u0449u0435u0441u0442u0432u0430u0434u043e mediator.;3.u0441u0443u0445u0430u00a0 biomass consortium u0431u0438u0444u0438u0434u043eu0431u0430u043au0442u0435u0440u0438u0439 strain of bifidobacterium adolescentis in - 1 and u043bu0430u043au0442u043eu0431u0430u0446u0438u043bu043b strain of lactobacillus acidophilus at 41 u0434u043bu00a0 u0438u0437u0433u043eu0442u043eu0432u043bu0435u043du0438u00a0 therapeutic drugs drugs, biologically active additives to food, food u043fu0438u0442u0430u043du0438u00a0, including the children's diet.the content of bifidobacterium adolescentis in - 1 from 108 to 1010 there and lactobacillus acidophilus at 41 from 108 to 1010 in some 1 g dry biomassu043fu043eu043bu0443u0447u0435u043du043du0430u00a0 by separate u043au0443u043bu044cu0442u0438u0432u0438u0440u043eu0432u0430u043du0438u00a0 u043bu0438u043eu0444u0438u043bu0438u0437u0438u0440u043eu0432u0430u043du043du044bu0445 cultures of strain of bifidobacterium adolescentis in - 1 synthetic nutritional environment and strain of lactobacillus acidophilus at - 41 organic nutritional environment to further separate the cultivation of crops u043au043eu043du0446u0435u043du0442u0440u0438u0440u043eu0432u0430u043du0438u0435u043c renewed, the obtained liquid biomass obtained one strain and mixing with a protective environmentthe separate drying method u0441u0443u0431u043bu0438u043cu0430u0446u0438u0438 and mixing of dry biomass.;4. method u043fu043eu043bu0443u0447u0435u043du0438u00a0 dry biomass of the u0431u0438u0444u0438u0434u043eu0431u0430u043au0442u0435u0440u0438u0439 strain of bifidobacterium adolescentis in - 1 and u043bu0430u043au0442u043eu0431u0430u0446u0438u043bu043b strain of lactobacillus acidophilus at 41 on p.3, u0445u0430u0440u0430u043au0442u0435u0440u0438u0437u0443u044eu0449u0435u0439u0441u00a0, u043bu0438u043eu0444u0438u043bu0438u0437u0438u0440u043eu0432u0430u043du043du044bu0435 culture strains of bifidobacterium and lactobacillus acidophilus adolescentis in - 1 at 41 are separate cultivation and strain Bifidobact erium adolescentis in 1 with the synthetic nutritional environment, strain of lactobacillus acidophilus at 41 with the organic breeding environmentthe reinvigorated culture subjected to further separation by liquid cultivation, the biomass of each strain concentrate is mixed with the protective environment and separately dried method u0441u0443u0431u043bu0438u043cu0430u0446u0438u0438 after which the dry biomass u0431u0438u0444u0438u0434u043eu0431u0430u043au0442u0435u0440u0438u0439 and u043bu0430u043au0442u043eu0431u0430u043au0442u0435u0440u0438u0439 mix to u043fu043eu043bu0443u0447u0435u043du0438u00a0 dry con u0441u043eu0440u0446u0438u0443u043cu0430.