NEW APPLICATION OF SUBSTITUTED AMINOMETHYRCHROMANES FOR TREATMENT OF MOVEMENT DISORDERS OR UNWANTED ACTIONS CAUSED BY MEANS FOR THE TREATMENT OF EXTRAPYRAMIDE MOVEMENT DISORDERS

摘要

Substituted aminomethyl chromans, one of their optical isomers or pharmaceutically acceptable salts, used for the manufacture of a medicament for the treatment of adverse effects of anti-Parkinsonian drugs in extrapyramidal movement disorders and/or for the manufacture of a medicament for the treatment of extrapyramidal symptoms (EPS) induced by neuroleptics. A preferred compound is (-)-(R)-2-{4-[[3,4-dihydro-2H-benzopyran-2-yl)-methyl!amino!butyl}-1,2-benzoisothiazol-3-(2H)-on-1,1-dioxide or a physiologically acceptable salt thereof.