EARLY DIAGNOSIS METHOD FOR DETECTING DISEASES RELATED TO CELLULAR GENETIC APPARATUS DISORDERS

摘要

FIELD: medicine.;SUBSTANCE: method involves taking blood sample and dividing it plasma and blood cells fraction. The blood cells fraction is divided into erythrocytes and leukocytes and extracellular nucleic acids bound to erythrocytes and leukocytes surface are eluted. Extracellular nucleic acids fraction is separated and amplification analysis of not less than two known specific nucleic acid sequences associated to particular disease by applying appropriate method (polymerase chain reaction, ligase chain reaction, multiplex polymerase chain reaction and others).;EFFECT: high accuracy of diagnosis.;6 cl, 1 dwg, 4 tbl