METHOD FOR EARLY AND PRECLINICAL DIAGNOSTICS OF CERVICAL CANCER

摘要

FIELD: medicinal biochemistry.;SUBSTANCE: the present innovation deals with detecting oncoprotein E7 of human papilloma virus (HPV) in biopsy sample with the help of the pairs of monoclonal antibodies referring to IgG2a and IgG2b groups chosen out of the following groups: 716-321, 716-325, 716-332, 716-343, 716-281, 716-288 one of which is indicated for primary protein binding and another, being the antibody conjugate with enzymatic label - to detect the complexes developed.;EFFECT: higher sensitivity of the method.;5 cl, 4 dwg, 4 ex, 2 tbl