BENZAMIDE DERIVATIVE-CONTAINING PHARMACEUTICAL COMPOSITION ELICITING ENHANCED SOLUBILITY AND ABSORPTION CAPACITY IN ORAL APPLYING

摘要

FIELD: chemical-pharmaceutical industry, pharmacy.;SUBSTANCE: invention relates to a new pharmaceutical composition comprising benzamide derivative and one or some additives taken among the following substances: 1) mixture of polyethylene glycol and surface-active substance; 2) amino acid or inorganic acid salt, and 3) propylene carbonate. The composition comprises benzamide derivative taken in the amount from 0.001 to 1000 mg per a single dosing formulation. The composition shows the enhanced solubility and absorption capacity in oral route of administration.;EFFECT: improved medicinal and pharmaceutical properties of composition.;9 cl, 4 tbl, 1 dwg, 5 ex