Apparatus and method for determination of the samples contained in the chemical or biochemical partners, more generally, receptor ligand systems - -

摘要

A device for the determination of in liquid samples contained in the chemical or biochemical partners of receptor - ligand - systems, in which the liquid sample by a channel (1) flows, the inside of a in a cylinder (6) guided piston (5) is formed and at least one outlet (2) of the channel (1) is provided, which in relation to a on an optical element (4) available surface area (3) is aligned;the optical element (4) an end termination of the piston (5) forms,the outlet (2) of the channel (1) and the oncoming flow area (3) at a distance apart from one another, as well as in the direction of flow of the liquid sample be explained below on the onflow surface (3) at least one receiving space (9) for the liquid sample is present,on the oncoming flow area (3) at least one partner of a receptor ligand - system - is immobilized;Fluorescence excitation light (10) for a to a partner of the receptor - ligand - system a marker substance bound by the optical element (4) by total reflection conditions, for the formation of a evanescent field in the region of the..