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Agents and methods for the treatment and prevention of TSE, as well as methods for the preparation of the agent

机译:用于治疗和预防TSE的药剂和方法,以及该药剂的制备方法

摘要

The invention relates to an agent or a pharmaceutical active substance and a method for the treatment, prevention and diagnosis of TSE and to a method for producing the agent or pharmaceutical active substance. According to the invention, peptides or nucleotide sequences coding for these peptides are provided, which are disclosed in the sequence reports 1 to 27 as well as partial sequences thereof. DOLLAR A With the peptides according to the invention a treatment or prevention of the disease TSE can be made, for example, in humans Creutzfeld-Jakob syndrome, Kuru, Gerstmann-Sträussler-Scheinker syndrome and FFI (Fatal Familial Insomnia). TSEs are known in animals, scrapie in sheep, BSE in cattle and CWD in wild animals.
机译:本发明涉及一种试剂或药物活性物质以及用于治疗,预防和诊断TSE的方法,并且涉及一种用于生产该试剂或药物活性物质的方法。根据本发明,提供了肽或编码这些肽的核苷酸序列,其在序列报告1-27及其部分序列中公开。 DOLLAR A用本发明的肽可以治疗或预防TSE疾病,例如在人类Creutzfeld-Jakob综合征,Kuru,Gerstmann-Strässler-Scheinker综合征和FFI(致命家族性失眠)中。 TSE在动物中是已知的,在绵羊中是痒痒病,在牛中是BSE,在野生动物中是CWD。

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