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use of prolactinmodulatoren and diet for the production of a drug for the treatment of obesity

机译:泌乳素调节剂和饮食在生产用于治疗肥胖症的药物中的用途

摘要

The present invention is directed to an improvement in a method of weight and/or body-fat reduction comprising a (preferably moderate) reduction in the caloric intake of a subject in need of such treatment in combination with administration to said subject of a prolactin inhibitor. Additionally, the present invention is directed to an improvement in a method for altering and/or resetting prolactin profiles (and thereby controlling one or more metabolic disorders such as obesity, excessive body fat, hyperlipidemia, hyperlipoproteinemia, hyperglycemia, hypercholesterolemia, hyperinsulinemia, insulin resistance, glucose intolerance, and Type II diabetes) comprising administration to a subject in need of such treatment of a prolactin inhibitor at a predetermined time or times during a 24-hour period in combination with a (preferably moderate) reduction of the caloric intake of said subject.
机译:本发明涉及减轻体重和/或减少体内脂肪的方法,该方法包括(优选适度地)减少需要这种治疗的受试者的热量摄入,并向所述受试者施用催乳激素抑制剂。 。另外,本发明针对用于改变和/或复位催乳素谱(并由此控制一种或多种代谢紊乱,例如肥胖,体脂过多,高脂血症,高脂蛋白血症,高血糖,高胆固醇血症,高胰岛素血症,胰岛素抵抗)的方法的改进,葡萄糖耐受不良和II型糖尿病),包括在24小时内的预定时间或一段时间内,对需要这种催乳素抑制剂治疗的受试者进行给药,同时(最好是适度地)降低所述患者的热量摄入学科。

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